Acta Pharm. 54 (2004) 13-26

Synthesis and antimicrobial evaluation of naphtho[2,1-b]pyrano[2,3-d]pyrimidine and pyrano[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives

FATHY A. EID, ASHRAF H. F. ABD EL-WAHAB, GAMEEL A. M. EL-HAG ALI
and  MOUSTAFA M. KHAFAGY

ash_abdelwahab@hotmail.com

Department of Chemistry, Faculty of Science, Al-Azhar University, Nasr City 11884 Cairo, Egypt

Several novel naphtho[2,1-b]pyrano[2,3-d]pyrimidines, pyrano[3,2-e][1,2,4]triazolo[1,5-c]pyrimidines and their coumarin-3-yl derivatives were synthesized. Some of these derivatives exhibited pronounced antimicrobial activities.

Keywords:pyranopyrimidine derivatives, pyranotriazolopyrimidine derivatives, coumarin-3-yl-pyranotriazolopyrimidine derivatives, antibacterial activity