Acta Pharm. 51 (2001) 147-151

Short communication  

Seasonal variations in the content and composition of the essential oil of Micromeria thymifolia (Scop.) Fritsch


1Department of Pharmacognosy, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia
2Irex-Aroma, Zagreb, Croatia
Received November 2, 2000      Accepted March 23, 2001

The yield of essential oil obtained by hydrodistillation from aerial parts of Micromeria thymifolia (Scop.) Fritsch varied from 0.3% to 0.5% (V/m) during vegetation period. The oils were characterised by a very high content of oxygenated monoterpenes (90.2-96.5%). Other components were monoterpene hydrocarbons and sesquiterpenes. Piperitenone oxide, pulegone and piperitone were identified as the major components of the investigated oils (GC, GC-MS). Significant seasonal variations in the relative amounts of the main components were confirmed. A continuous reduction in the oxide fraction with an accompanying increase in the proportion of ketones was observed.

Keywords: Micromeria thymifolia (Lamiaceae), essential oil, piperitenone oxide, pulegone, piperitone