Acta Pharm. 53 (2003) 295-303

X-ray powder diffraction patterns for certain fluoroquinolone antibiotic drugs

SUBBIAH THANGADURAI,^1*  SUDHIR KUMAR SHUKLA,²  ASIM KUMAR SRIVASTAVA²  and YERRAMILLI ANJANEYULU³ 

kalankathanga@hotmail.com or goldaurium@yahoo.co.in

¹Department of Geology & Mining, Guindy, Chennai - 600 032, India
²Central Forensic Science Laboratory, BPR & D, Hyderabad - 500 028, India
³Centre for Environment, IPGS & R, JNT University, Hyderabad - 500 028, India

X-ray powder diffraction (XRD) data for six pure fluoroquinolone antibiotic drugs, ciprofloxacin, norfloxacin, enrofloxacin, ofloxacin, pefloxacin and sparfloxacin, have been obtained using a powder diffractometer. The drugs were scanned from a Bragg angle of 10° to 70°. The obtained data were tabulated in terms of the lattice spacing (angstrem) and relative line intensities (I/I_I). This new information may be useful for the identification of these drugs.

Keywords: fluoroquinolones, antibiotic drugs, identification, X-ray diffraction, powder