Acta Pharm. 55 (2005) 321-326

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Short communication 

Essential oil of the Persian sage, Salvia rhytidea Benth.


1Isfahan Pharmaceutical Research Center, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran
2Department of Pharmacognosy, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran
Received September 27, 2004      Accepted May 24, 2005

Chemical composition of volatile compounds from Salvia rhytidea Benth. was analyzed, for the first time, by gas chromatography/mass spectrometry. The volatiles were isolated from dried aerial parts of the plant by hydro-distillation. A total yield of 2.0 mg of essential oil per g of plant dry mass was obtained and sixty compounds were identified, representing 98.2% of total volatiles. The essential oil was characterized by a high content of hydrocarbon and oxygenated monoterpenes. The main constituents were p-cymene-8-ol (11.9%), spathulenol (7.3%), pulegone (6.4%), sabinene (5.8%), terpinen-4-ol (5.5%) and alpha-copaene (5.3%).

Keywords: Salvia rhytidea (Lamiaceae), essential oil, p-cymene-8-ol, spathulenol, pulegone