Acta Pharm. 56 (2006) 369-374

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Synthesis and spectroscopic data analyses of 5beta-cholane derivatives

LUTFUN NAHAR, 1 SATYAJIT D. SARKER2 AND ALAN B. TURNER1

lnahar2003@yahoo.co.uk

1Japp Laboratory, Department of Chemistry, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, Scotland, UK
2 School of Biomedical Sciences, University of Ulster at Coleraine, Cromore Road, Coleraine BT52 1SA, Co. Londonderry, Northern Ireland, UK
Accepted April 19, 2006

Facile synthesis and spectroscopic data analyses of three 5beta-cholane derivatives, 3alpha-tosyloxy-5beta-cholan-24-ol (3), 5beta-cholan-24-ol (4) and 5beta-cholan-24-yl tosylate (5), are described.


Keywords: steroids, lithocholic acid, reduction, tosylation, NMR