Acta Pharm. 55 (2005) 409-415

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Short communication 
 

Investigation of antimicrobial activity of Pelargonium radula (Cav.) L'Hérit

STJEPAN PEPELJNJAK1*, ZDENKA KALODJERA2 and  MARIJANA ZOVKO2

spep@yahoo.com

1Department of Microbiology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia
2Department of Pharmacognosy, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia
Received May 20, 2005      Accepted July 20, 2005

Antimicrobial activities of two ethanolic extracts made from fresh and dried leaves of Pelargonium radula (Cav.) L'Hérit, were tested against fourteen species of bacteria and fifteen species of fungi. The well-diffusion method indicated the strongest activity against Pseudomonas aeruginosa. The broth dilution method revealed that the most sensitive microorganisms were Bacillus pumilus, Bacillus subtilis, Escherichia coli and Serratia marcescens. Extract prepared from fresh leaves showed significantly higher antimicrobial activity than the extract prepared from dried leaves.


Keywords: Pelargonium radula, ethanolic extract, well-diffusion method, dilution method, antimicrobial activity