Acta Pharm. 54 (2004) 57-63

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Short communication 
 

Steroids and polyketides from Uvaria hamiltonii stem bark

KAMRUN NAHAR ASHA, RASHEDUZZAMAN CHOWDHURY,* CHOUDHURY M. HASAN and MOHAMMAD A. RASHID

rzchy@dhaka.net

Phytochemical Research Laboratory, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
Received September 2, 2003      Accepted February 16, 2004

Two known steroids, stigmasterol and 6beta-hydroxystigmasta-4,22-dien-3-one (1) and two unusual polyketides, cis-4-hydroxymellein (2) and trans-4-hydroxymellein (3) were isolated from the stem bark of Uvaria hamiltonii. The structures of the compounds were elucidated independently by high-resolution 2D-NMR techniques and confirmed by comparison with previously reported values.


Keywords: Uvaria hamiltonii (Annonaceae), polyketides