Acta Pharm. 69 (2019) 585-606
Original research paper
Implementation of
medication management services at the primary healthcare level – a pilot study
ANDREA BRAJKOVIĆ, IVA MUCALO, TONI VIDOVIĆ, MARIANA MARTINS GONZAGA DO
NASCIMENTO, ANTONIJA BALENOVIĆ, INO PROTRKA and DJENANE RAMALHO DE OLIVEIRA
imucalo@pharma.hr
1 University of Zagreb Faculty of
Pharmacy and Biochemistry, Zagreb, Croatia
2 Zagreb City Pharmacy, Zagreb,
Croatia
3 Centre for Pharmaceutical Care
Studies (Centro de Estudos Atencao Farmaceutica), Federal University of Minas
Gerais, Belo Horizonte, MG, Brazil
4 Health Centre Zagreb – Centre,
Zagreb, Croatia
Accepted July 23, 2019
Published online September 6, 2019
This study
employed a mixed-method approach to enable the implementation of comprehensive
medication management (CMM) services in Croatia’s primary care setting. Drug
therapy problems (DTPs) and factors associated with their occurrence were
determined in patients with chronic diseases from January 2018 to April 2019.
The pre-implementation stage established the foundations for the early
implementation stage, in which the practice was set up, the patients'
recruitment initiated and various challenges identified. During the study
period, 86 patients were recruited for CMM provision. Overall, 2.8 DTPs (± 1.6)
per patient were identified and the majority (96.2 %) presented with at least
one DTP. Multiple regression analysis showed that type 2 diabetic patients (p = 0.025) and patients using five or
more medications (p = 0.011) should
be prioritized to receive CMM services as potentially they have a higher number
of DTPs, and could, therefore, obtain a greater
benefit from the service.
Keywords: comprehensive
medication management services, drug therapy problems, risk factors,
pharmaceutical care, primary care, implementation stage